Liver Microenvironment

My research interests are in understanding the role of the immune microenvironment in disease settings. I have previously studied the role of the immune microenvironment in tumour progression and in solid organ transplantation, primarily using rodent models. In collaboration with the Humanized Mouse Unit at the Institute of Molecular and Cell Biology, I am currently characterizing a humanized mouse model of hepatitis B virus (HBV) infection. The aim is to better understand the phenotypic and functional changes in the immune system during chronic HBV infection in order to develop a model system for testing potential therapies.